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Side Effects of Aliskiren

Common side effects of aliskiren include diarrhea, coughing, and a rash. These side effects are generally minor and easily treated. However, more serious side effects can occur. Make sure to notify your healthcare provider right away if you are experiencing aliskiren side effects such as fainting spells; seizures; or swelling of the lips, mouth, tongue, or throat.

An Introduction to Side Effects of Aliskiren

As with any medicine, aliskiren hemifumarate (Tekturna®) can cause side effects. However, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with aliskiren. Your healthcare provider can discuss a more complete list of aliskiren side effects with you.)

Serious Side Effects of Aliskiren

Aliskiren has been studied thoroughly in clinical trials. In these studies, one group of people received the real medication, while another group was given a placebo (a "sugar pill" that does not contain any active ingredients). From these studies, it is possible to see what side effects occurred, how often they appeared, and how they compared to the group who took the placebo.
Some side effects with aliskiren, while usually infrequent, are potentially serious and should be reported immediately to your healthcare provider. Some of these side effects are so rare that it is difficult to know whether they are caused by aliskiren or other factors. Serious side effects of aliskiren include but are not limited to:
  • Swelling of the lips, mouth, tongue, or throat (known medically as angioedema)
  • Dizziness, lightheadedness, or fainting, which may be signs of low blood pressure (hypotension)
  • Kidney stones
  • Seizures
  • Signs of high potassium levels (hyperkalemia), such as:
    • Abnormal sensations, such as burning, tingling, or pricking
    • Muscle weakness
    • A low heart rate (bradycardia)
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
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Aliskiren Drug Information

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