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More Information on Amlodipine and Atorvastatin Interactions

More Information on Amlodipine and Atorvastatin Interactions

The following sections explain in detail the potentially negative interactions that can occur when amlodipine and atorvastatin is combined with any of the substances listed above. Because the amlodipine (Norvasc®) component is unlikely to interact with most other medications, the interactions discussed in this article are primarily due to the atorvastatin (Lipitor®) component.
 
Antacids
If you are using antacids while on amlodipine and atorvastatin, make sure to take the antacid at least two hours before or after taking your amlodipine and atorvastatin dose. Antacids may decrease the level of atorvastatin (one of the components) in your blood, perhaps making it less effective.
 
Birth Control Pills
Taking birth control pills with amlodipine and atorvastatin can increase the level of the hormones in the pills, perhaps increasing your risk of side effects. Be sure to discuss this with your healthcare provider if you are currently using birth control pills. He or she may recommend a birth control pill with a lower dose of hormones.
 
Certain Antibiotics or Antifungals
Some antibiotics and antifungal medications can increase the level of atorvastatin in your blood, possibly increasing your risk of side effects -- including myopathy or rhabdomyolysis (see Lipitor and Muscle Pain). In addition, combining amlodipine and atorvastatin with ketoconazole can theoretically increase your risk of low hormone levels. Talk with your healthcare provider before using these medications together.
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