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Pediatric and Off-Label Uses for Amlodipine and Atorvastatin

How Does Amlodipine and Atorvastatin Work?

Amlodipine, one of the components, is part of a class of drugs called calcium channel blockers. It helps slow down the rate at which calcium moves into your heart and into the blood vessel walls. This, in turn, helps to relax the vessels, which allows for better blood flow and causes lower blood pressure. It also makes it easier for the heart to pump blood.
 
The other component, atorvastatin, belongs to a group of medications called statins (or HMG-CoA reductase inhibitors). It works by blocking a particular enzyme -- HMG-CoA reductase -- that controls the rate of cholesterol production in the body. This causes the liver to make less cholesterol. The medication also:
 

Is Amlodipine and Atorvastatin Used in Children?

Amlodipine has not been studied in children younger than six years old. Atorvastatin has not been studied in children under ten years old. The combination of the two has not been studied in any children. Be sure to talk with your healthcare provider about the potential benefits and risks of using amlodipine and atorvastatin in children.
 

Is Amlodipine and Atorvastatin Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend amlodipine and atorvastatin for something other than the conditions discussed in this article. At this time, there are no universally accepted off-label amlodipine and atorvastatin uses.
 
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