ACE inhibitors, ARBs, and medicines that contain potassium are some of the drugs that may potentially interact with amlodipine and olmesartan. Drug interactions may affect the levels of medicines in your blood, possibly increasing your risk of side effects (such as high levels of potassium in your blood or dangerously low blood pressure). To help prevent drug interactions with amlodipine and olmesartan, make sure to tell your healthcare provider about any other medications you are taking.