Products That Interfere With Amlodipine and Valsartan
Amlodipine and Valsartan Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when amlodipine and valsartan is combined with any of the drugs listed above.
Combining amlodipine and valsartan with ACE inhibitors can increase your risk of high potassium levels in your blood (hyperkalemia). Your healthcare provider should check your potassium levels regularly (see Exforge and High Potassium for more information).
Drinking alcohol while taking amlodipine and valsartan can increase your risk of low blood pressure, especially when sitting or standing up suddenly. Talk to your healthcare provider about combining alcohol with amlodipine and valsartan.
Combining amlodipine and valsartan with aliskiren may increase the risk of dangerously low blood pressure (hypotension), fainting, kidney problems (including kidney failure), and dangerously high potassium levels in the blood (hyperkalemia). In general, such combinations are usually avoided. If it is necessary to take such medications together, very close monitoring will be required.
Aliskiren and this medication should never be combined in people with diabetes, because they may have a higher risk for these complications. Also, this combination is not recommended for people with moderate-to-severe kidney problems.
Amiloride (Midamor) or Amiloride-HCTZ (Moduretic)
Amlodipine and valsartan may interact with amiloride. Taking these two medications together increases your risk of high potassium levels (hyperkalemia).
Angiotensin II Receptor Blockers (ARBs)
Combining amlodipine and valsartan with ARBs can increase your risk of high potassium levels in your blood (hyperkalemia). Your healthcare provider should check your potassium levels regularly.
Amlodipine may increase the level of cyclosporine in the blood, perhaps increasing the risk for side effects. Because it is important for cyclosporine levels to fall within a certain range, your healthcare provider may need to check your blood levels and adjust your cyclosporine dosage if you start or stop taking amlodipine.