Drug Interactions With Amlodipine and Valsartan

Medications that may cause drug interactions with amlodipine and valsartan include amiloride, eplerenone, and ACE inhibitors. When certain medicines interact with the blood pressure medication, the drugs may lose their effectiveness and side effects may occur, such as low blood pressure or high potassium levels. To help prevent amlodipine and valsartan interactions, make sure your healthcare provider knows about all other medications you are taking.

Amlodipine and Valsartan Drug Interactions: An Overview

 Amlodipine and valsartan (Exforge®) can potentially interact with a few other medications. Some of these medicines that may lead to amlodipine and valsartan interactions include:
 
  • ACE inhibitors, such as:
o Eprosartan (Teveten®)
o Valsartan (Diovan®)
  • Digoxin (Digitek®, Lanoxin®)
  • Eplerenone (Inspra®)
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
o Ibuprofen (Motrin®, Advil®)
o Indomethacin (Indocin®, Indocin SR®)
  • Potassium-containing products, such as:
o Potassium chloride (K-Dur®, Klor-Con®, Micro-K®)
o Potassium citrate (Urocit-K®, Polycitra-K®)
o Potassium gluconate
o Potassium phosphate (Neutra-Phos-K®, K-Phos®)
o Salt substitutes (used to flavor food)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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