Side Effects of Amlodipine and Valsartan

Common side effects of amlodipine and valsartan that were seen in clinical studies include upper respiratory tract infections, swelling, and sore throat or stuffy nose. Nausea, dry mouth, and fatigue are some rare but possible side effects that have also been reported with amlodipine and valsartan. Side effects that are potentially serious and should be reported to a healthcare provider include anxiety, depression, and arrhythmia.

 

Amlodipine and Valsartan Side Effects: An Introduction

As with any medicine, side effects are possible with amlodipine and valsartan (Exforge®). However, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with amlodipine and valsartan. Your healthcare provider can discuss a more complete list of side effects with you.)
 

Possible Side Effects of Amlodipine and Valsartan

Amlodipine and valsartan has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and then compared to the side effects that occur in another group of people not taking the medicine. As a result, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
 
In these studies, the most common side effects of amlodipine and valsartan included:
 
  • Swelling or water retention, especially in the lower legs, ankles, or feet -- in up to 5.4 percent of people
  • A sore throat and a runny or stuffy nose -- up to 4.3 percent
  • Upper respiratory tract infections (such as the common cold) -- up to 2.9 percent
  • Dizziness -- up to 2.1 percent.
     
(Side Effects of Amlodipine and Valsartan Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;