Drugs That React With Amlodipine-Valsartan-Hydrochlorothiazide
Amlodipine-Valsartan-Hydrochlorothiazide Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when amlodipine-valsartan-hydrochlorothiazide is combined with any of the drugs listed above.
Combining amlodipine-valsartan-hydrochlorothiazide with ACE inhibitors can increase your risk of high potassium levels in your blood (hyperkalemia). Your healthcare provider should check your potassium levels regularly.
Drinking alcohol while taking amlodipine-valsartan-hydrochlorothiazide can increase your risk of low blood pressure, especially when sitting or standing up suddenly. Talk to your healthcare provider about combining alcohol with amlodipine-valsartan-hydrochlorothiazide.
Combining amlodipine-valsartan-hydrochlorothiazide with aliskiren may increase the risk of dangerously low blood pressure (hypotension), fainting, kidney problems (including kidney failure), and dangerously high potassium levels in the blood (hyperkalemia). In general, such combinations are usually avoided. If it is necessary to take such medications together, very close monitoring will be required.
Aliskiren and amlodipine-valsartan-hydrochlorothiazide should never be combined in people with diabetes, because they may have a higher risk for these complications. Also, this combination is not recommended for people with moderate-to-severe kidney problems.
Amiloride or Amiloride-HCTZ
Amlodipine-valsartan-hydrochlorothiazide may interact with amiloride. Taking these two medications together increases your risk of high potassium levels (hyperkalemia).
Angiotensin II Receptor Blockers (ARBs)
Amlodipine-valsartan-hydrochlorothiazide contains an ARB medication (valsartan). Combining amlodipine-valsartan-hydrochlorothiazide with other ARBs can increase your risk of high potassium levels in your blood (hyperkalemia). Your healthcare provider should check your potassium levels regularly.