Side Effects of Amlodipine-Valsartan-Hydrochlorothiazide

Common Side Effects

Amlodipine-valsartan-hydrochlorothiazide has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and compared to side effects seen in another group taking other blood pressure drugs. This way, it is possible to see what side effects occur, how often they appear, and how the two groups compare.
 
In these studies, the most common amlodipine-valsartan-hydrochlorothiazide side effects included:
 
  • Dizziness -- in up to 8.2 percent of people
  • Swelling or water retention of the hands, ankles, lower legs, or feet -- up to 6.5 percent
  • Headache -- up to 5.2 percent
  • Indigestion or heartburn -- up to 2.2 percent
  • Fatigue -- up to 2.2 percent
  • Muscle spasms -- up to 2.2 percent.
     
Other common side effects (all occurring in 2.1 percent of people) included:
 

Rare Side Effects

There are other possible side effects with amlodipine-valsartan-hydrochlorothiazide that can occur. These rare side effects occur in less than 0.2 percent of people. For these side effects, it is difficult to tell whether they are actually caused by the medication itself or something else.
 
Some of these rare but possible side effects include, but are not limited to:
 
(Side Effects of Amlodipine-Valsartan-Hydrochlorothiazide Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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