What Is Amlodipine-Valsartan-Hydrochlorothiazide Used For?

How Does It Work?

Amlodipine-valsartan-hydrochlorothiazide contains three different medications. Amlodipine is a calcium channel blocker that helps to slow down the rate at which calcium moves into your blood vessel walls. This, in turn, helps to relax the vessels, which allows better blood flow and causes lower blood pressure.
 
Valsartan belongs to a class of drugs called angiotensin II receptor blockers. Angiotensin II is a naturally occurring chemical in the body that causes blood vessels to narrow (constrict). By blocking angiotensin II, valsartan helps to relax the blood vessels, lowering blood pressure.
 
Hydrochlorothiazide is a diuretic, which is commonly referred to as a "water pill." It works by increasing the amount of salt and water that the kidneys remove from the blood. This extra salt and water is passed out through the urine.
 
This action causes a decrease in blood volume. Because of this effect, hydrochlorothiazide can lower blood pressure and also help with water retention.
 

Can Children or Teens Use It?

Amlodipine-valsartan-hydrochlorothiazide is not approved for use in children or teens. Talk with your child's healthcare provider about the benefits and risks of using this drug in children.
 

Off-Label Uses

On occasion, your healthcare provider may recommend amlodipine-valsartan-hydrochlorothiazide for treating something other than high blood pressure. At this time, however, there are no universally accepted off-label uses for this product.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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