Drugs That Can Interact With Azilsartan/Chlorthalidone
More Detail on Drug Interactions With Azilsartan/ChlorthalidoneThe following sections explain in detail the potentially negative interactions that can occur when azilsartan/chlorthalidone is combined with any of the drugs listed above.
Drinking alcohol while taking azilsartan/chlorthalidone may cause your blood pressure to decrease too much. If you consume alcohol while taking this medication, watch for symptoms of low blood pressure, such as dizziness, lightheadedness, or fainting, especially while standing from a seated position. Contact your healthcare provider if you experience these symptoms.
Combining azilsartan-chlorthalidone with aliskiren may increase the risk of dangerously low blood pressure (hypotension), fainting, kidney problems (including kidney failure), and dangerously high potassium levels in the blood (hyperkalemia). In general, such combinations are usually avoided. If it is necessary to take such medications together, very close monitoring will be required.
Aliskiren and azilsartan-chlorthalidone should never be combined in people with diabetes, because they may have a higher risk for these complications. Also, this combination is not recommended for people with moderate-to-severe kidney problems.
Taking azilsartan/chlorthalidone within 24 hours of receiving amifostine could cause your blood pressure to lower to unsafe levels. Talk to your healthcare provider about this possible interaction if you receive amifostine treatment.
Combining azilsartan/chlorthalidone with an ACE inhibitor may increase the risk for certain side effects, such as high blood potassium, kidney problems, or very low blood pressure.