Benazepril

Benazepril has been licensed to treat high blood pressure. The medication causes blood vessels to relax, which can help lower blood pressure. In clinical studies, benazepril reduced systolic blood pressure by 6 to 12 mmHg and diastolic blood pressure by 4 to 7 mmHg. The most common side effects include headache, dizziness, and fatigue.

What Is Benazepril?

Benazepril hydrochloride (Lotensin®) is a prescription medication that has been licensed for controlling high blood pressure (hypertension) in adults and children six years of age and older. The medication does not cure high blood pressure.
 
Benazepril is part of a class of drugs called angiotensin-converting enzyme inhibitors, or ACE inhibitors for short.
 
(Click Benazepril Uses for more information, including possible off-label uses.)
 

Who Makes It?

Benazepril is manufactured by Novartis Pharmaceuticals.
 

How Does It Work?

The medication is part of a class of drugs called ACE inhibitors. ACE stands for angiotensin-converting enzyme. Benazepril helps to block this enzyme, which is normally part of a reaction in the body that causes the blood vessels to narrow (constrict). By blocking this enzyme, the medication causes blood vessels to relax, which can lower blood pressure.
 

Effects of Benazepril

A
 blood pressure reading consists of two numbers -- for example: 120/80. The top number is known as the systolic blood pressure and the bottom number is the diastolic blood pressure. During clinical studies in people taking benazepril, systolic blood pressure decreased, on average, by 6 to 12 mmHg and diastolic blood pressure decreased by 4 to 7 mmHg, on average. The higher the dose, the greater the drop in blood pressure tended to be.
 
By lowering blood pressure, the medication can decrease the risks that accompany long-term high blood pressure (see Effects of High Blood Pressure).
 

When and How Do I Take It?

Some general considerations for when and how to take benazepril include the following:
 
  • The medication comes in tablet form. It is usually taken once or twice a day.
     
  • Benazepril can be taken with or without food.
      
  • The medication should be taken at the same time each day to maintain an even level in your blood.
     
  • If you have difficulty swallowing the tablet, talk to your pharmacist or healthcare provider about taking a different form of benazepril.
     
  • For benazepril to work properly, you have to take it as prescribed. The medication will not work if you stop taking it.
     

Dosing Information

The dose of benazepril your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • Your age
  • Other medical conditions you may have
  • Other medications you may be taking.
     
As with any medication, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 
(Click Benazepril Dosing for more information.)
 

Side Effects of Benazepril

As with any medicine, side effects are possible with benazepril. However, not everyone who takes it will experience side effects. If they do occur, side effects are often minor, meaning they require no treatment or are easily treated by you or your healthcare provider. Serious side effects are less common.
 
The most common side effects include:
 
(Click Benazepril Side Effects to learn more, including serious side effects you should report to your healthcare provider.)
 
You can also read about other possible side effects in the following eMedTV articles:
 

Drug Interactions

Benazepril can potentially interact with a number of medicines (see Drug Interactions With Benazepril for more information).
 

What Should I Tell My Healthcare Provider?

Prior to taking benazepril, you should tell your healthcare provider if you have:
 
Also, let your healthcare provider know if you:
 
  • Are pregnant or trying to become pregnant (see Lotensin and Pregnancy)
  • Are breastfeeding
  • Are on dialysis
  • Will be undergoing surgery or anesthesia.
     
Tell your healthcare provider about all the medicines you are currently taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
Do not take any salt substitutes containing potassium or potassium supplements without first discussing it with your healthcare provider.
 
(Click Warnings and Precautions With Benazepril to learn more, including information on who should not take the drug.)
 

What If I Take an Overdose?

People who take too much benazepril may have overdose symptoms that could include extremely low blood pressure.
 
If you happen to take too much, seek immediate medical attention.
 
(Click Lotensin Overdose for more information.)
 

How Should Benazepril Be Stored?

Benazepril should be stored at room temperature, away from moisture and heat. The tablets should be kept in an airtight container.
 
Keep this and all medications out of the reach of children.
 

What Should I Do If I Miss a Dose?

If you do not take your benazepril as scheduled, take your missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with normal dosing. Never take a double dose.
 

Available Strengths

Benazepril tablets are available in several strengths, including:
 
  • Benazepril 5 mg
  • Benazepril 10 mg
  • Benazepril 20 mg
  • Benazepril 40 mg.
     

Generic Benazepril

Benazepril is available as a generic medicine (see Generic Benazepril for more information).
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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