Benazepril

The prescription drug benazepril has been licensed to treat high blood pressure. Like other ACE inhibitors, benazepril causes blood vessels to relax, which can help lower blood pressure. In previous clinical studies, benazepril reduced systolic blood pressure by an average of 6 to 12 mmHg and diastolic blood pressure by an average of 4 to 7 mmHg. The most common side effects of benazepril include headache, dizziness, and fatigue. You should not adjust your dose of benazepril unless your doctor specifically instructs you to do so.

 

What Is Benazepril?

Benazepril hydrochloride (Lotensin®) is a prescription medication that has been licensed for controlling high blood pressure (hypertension) in adults and children six years of age and older. Benazepril does not cure high blood pressure.
 
Benazepril is part of a class of drugs called angiotensin-converting enzyme inhibitors, or ACE inhibitors for short.
 
(Click Benazepril Uses for more information on benazepril uses, including possible off-label uses.)
 

Who Makes Benazepril?

Benazepril is manufactured by Novartis Pharmaceuticals.
 

Benazepril: How Does It Work?

Benazepril is part of a class of drugs called ACE inhibitors. ACE stands for angiotensin-converting enzyme. Benazepril helps to block the angiotensin-converting enzyme, which is normally part of a reaction in the body that causes the blood vessels to narrow (constrict). By blocking this enzyme, benazepril causes blood vessels to relax, which can lower blood pressure.
 

Benazepril Effects

A
 blood pressure reading consists of two numbers -- for example: 120/80. The top number is known as the systolic blood pressure and the bottom number is the diastolic blood pressure. During clinical studies in people taking benazepril, systolic blood pressure (the top number) decreased (on average) by 6 to 12 mmHg and diastolic blood pressure (the bottom number) decreased by 4 to 7 mmHg (on average). The higher the dose of benazepril, the greater the drop in blood pressure tended to be.
 
By lowering blood pressure, benazepril can decrease the risks that accompany long-term high blood pressure (see Effects of High Blood Pressure).
 
(Benazepril Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;