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Is Bisoprolol Safe?

Common Side Effects

Bisoprolol has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and compared to those that occur in another group of people not taking the medicine. This way, it is possible to see what problems occur, how often they appear, and how they compare to the group not taking the medicine.
In these studies, the most common bisoprolol side effects (occurring more frequently with bisoprolol than with the placebo) included:
  • Fatigue -- in up to 8.2 percent of people
  • Upper respiratory infection (such as the common cold) -- up to 5 percent
  • Runny or stuffy nose -- up to 4 percent
  • Dizziness -- up to 3.5 percent
  • Diarrhea -- up to 3.5 percent.
Other common side effects (occurring in 1 to 2.7 percent of people) included:
  • Joint pain
  • Decreased sensation (such as a decreased sense of touch)
  • Insomnia
  • Nausea
  • Vomiting
  • Sinus infection or irritation
  • General weakness.

Other Possible Bisoprolol Side Effects

Some side effects with bisoprolol were not seen during clinical studies in the United States, but were reported in patients after the medication was approved or in clinical studies outside the United States. Thus, it is difficult to know for sure if these problems are caused by bisoprolol or unrelated factors. These possible side effects include:
  • A spinning sensation (vertigo)
  • Drowsiness
  • Anxiety
  • Memory problems
  • Dry mouth
  • Indigestion or heartburn
  • Constipation
  • Muscle pain or twitching
  • Acne
  • Eczema
  • Sweating
  • Hair loss
  • Ringing in the ears (tinnitus)
  • Hearing loss.
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Bisoprolol Drug Information

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