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Drugs That React With Bisoprolol

Bisoprolol Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when bisoprolol is combined with any of the drugs listed above.
 
Alpha Blockers
Taking bisoprolol with an alpha blocker can increase the risk of dangerously low blood pressure (hypotension). Check with your healthcare provider before combining such medications.
 
Calcium Channel Blockers
Combining bisoprolol with certain calcium channel blockers may cause dangerously low blood pressure and, for verapamil or diltiazem, a slow heart rate (bradycardia) and heart failure. You may need to be monitored closely if you take these medications together. In some cases, bisoprolol should not be taken with a calcium channel blocker.
 
Certain Arrhythmia Medications
Taking bisoprolol with certain arrhythmia medications may cause a dangerously slow heart rate (bradycardia). You may need to be monitored closely if you take these medications together. In some cases, bisoprolol and an arrhythmia medication should not be combined.
 
Clonidine
If you take clonidine and bisoprolol, stopping clonidine (without stopping bisoprolol) could increase the risk of dangerously high blood pressure, strokes, and other serious problems. People are generally advised to stop taking bisoprolol several days before gradually reducing the dose of clonidine. Do not attempt this without the approval and supervision of your healthcare provider.
 
Digoxin
Combining bisoprolol with digoxin may cause a dangerously slow heart rate (bradycardia). You may need to be monitored closely if you take these medications together. In some cases, bisoprolol and digoxin should not be taken together.
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Bisoprolol Drug Information

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