Drug Interactions With Candesartan-Hydrochlorothiazide

More Detail About Candesartan-Hydrochlorothiazide Interactions

Diuretics
When taking candesartan-hydrochlorothiazide with a diuretic, your blood pressure may decrease too much. This is more likely to occur when candesartan-hydrochlorothiazide is first started. In order to decrease the chances of this interaction, your healthcare provider may start you on a lower dose of candesartan-hydrochlorothiazide and/or monitor you more closely.
 
Potassium Supplements or Salt Substitutes With Potassium
If you are taking candesartan-hydrochlorothiazide along with a potassium supplement or a salt substitute with potassium, the levels of potassium in your blood may become too high. This can cause serious problems. For your particular situation, talk to your healthcare provider about using potassium and candesartan-hydrochlorothiazide together.
 
Potassium-Sparing Diuretics
If you are taking both candesartan-hydrochlorothiazide and a potassium-sparing diuretic, your body may metabolize them differently than intended and/or increase the levels of potassium in your blood. Your healthcare provider may choose to monitor your progress more closely.
 
Lithium (Eskalith, Lithane, Lithonate, Lithotabs)
If you are taking both candesartan-hydrochlorothiazide and lithium, your body may metabolize the drugs differently than intended and increase the lithium levels in the blood. Your healthcare provider may choose to monitor your serum lithium levels more frequently.
 
Insulin
Taking insulin with candesartan-hydrochlorothiazide may cause high blood sugar (hyperglycemia). For your particular situation, your healthcare provider may monitor you more closely and/or adjust your dose of insulin as needed.
(Drug Interactions With Candesartan-Hydrochlorothiazide Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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