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More Info on Candesartan-Hydrochlorothiazide Interactions

Colestipol (Colestid)
Colestipol can bind to candesartan-hydrochlorothiazide in the digestive tract and decrease its absorption into the body. To avoid this drug interaction, candesartan-hydrochlorothiazide should be taken at least one hour before, or four to six hours after, colestipol has been given.
 
Corticosteroids
Taking corticosteroids with candesartan-hydrochlorothiazide may cause an electrolyte imbalance, especially with the levels of potassium in the blood. If you are taking a corticosteroid with candesartan-hydrochlorothiazide, your healthcare provider may monitor you more closely and/or adjust your dose of medicine as needed.
 
Norepinephrine
Norepinephrine is a medicine that is used to treat very low blood pressure. Candesartan-hydrochlorothiazide may affect the ability of norepinephrine to raise blood pressure.
 
Corticotropin
Taking corticotropin with candesartan-hydrochlorothiazide may cause an electrolyte imbalance, especially with the levels of potassium in the blood. If you are taking corticotropin with candesartan-hydrochlorothiazide, your healthcare provider may monitor you more closely and/or adjust your dose as needed.
 
Muscle Relaxants
If you are taking both candesartan-hydrochlorothiazide and a muscle relaxant, your body may metabolize the drugs differently than intended and increase the muscle relaxant levels in the blood. In order to decrease the chances of this drug interaction, your healthcare provider may monitor you more closely and/or change the muscle relaxant dose.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Candesartan-hydrochlorothiazide can interact with NSAIDs in several ways. The combination could cause your blood pressure to increase or may cause swelling (edema), especially if you have congestive heart failure (CHF). If you are elderly, have kidney disease or kidney failure, or are taking a diuretic ("water pill") or are dehydrated, taking NSAIDs and candesartan-hydrochlorothiazide together may cause kidney failure. Talk to your healthcare provider about this potential drug interaction before taking these medications together.
  
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