Cardene SR Drug Interactions

When medicines such as cimetidine or cyclosporine are taken together with Cardene SR, drug interactions may occur. These interactions can increase your risk of developing side effects. Your healthcare provider may need to monitor the level of the medications in your blood and adjust your dosages as necessary. Prior to taking Cardene SR, be sure to talk to your healthcare provider about potential drug interactions that may apply to you.

 

An Overview of Cardene SR Drug Interactions

Cardene SR® (nicardipine SR) can potentially interact with a few other medicines. Some of these medicines that may lead to Cardene SR drug interactions include:
 

Cardene SR Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Cardene SR is combined with any of the drugs listed above.
 
Cimetidine (Tagamet)
Cimetidine may increase the level of Cardene SR in your blood, increasing your risk of Cardene SR side effects. Your healthcare provider may need to adjust your Cardene SR dose or may suggest an alternative to cimetidine.
 
Cyclosporine (Gengraf, Neoral, Sandimmune)
Taking cyclosporine with Cardene SR can increase the level of cyclosporine in your blood, increasing your risk of side effects. Your healthcare provider should carefully monitor the level of cyclosporine in you blood, adjusting your dose as necessary.
 

Final Thoughts on Cardene SR Drug Interactions

It is possible that not every Cardene SR drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about drug interactions with Cardene SR that may apply to your situation.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;