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Specific Drugs That React With Catapres-TTS

Catapres-TTS Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Catapres-TTS is combined with any of the drugs listed above.
 
Beta Blockers
Combining Catapres-TTS with a beta blocker can increase the risk of dangerously low blood pressure (hypotension) or a dangerously slow heart rate (bradycardia). However, in many cases, such combinations can be safe and effective. Check with your healthcare provider before combining such medications.
 
If you take both Catapres-TTS and a beta blocker, stopping the Catapres-TTS (without stopping the beta blocker) could increase the risk of dangerously high blood pressure, strokes, and other serious problems. It is advised to stop taking the beta blocker several days before you gradually reduce the dose of Catapres-TTS. Do not attempt this without the approval and supervision of your healthcare provider.
 
Certain Calcium Channel Blockers
Combining Catapres-TTS with certain calcium channel blockers may cause a dangerously low blood pressure and a slow heart rate (bradycardia). You may need to be monitored very closely if you take these medications together.
 
Digoxin
Combining Catapres-TTS with digoxin may cause a dangerously slow heart rate (bradycardia). You may need to be monitored very closely if you take these medications together.
 
Other Medications That Cause Drowsiness
Catapres-TTS should be combined with other sedating medications or substances cautiously. Check with your healthcare provider before taking such medications together. Additionally, many antidepressants may decrease the effectiveness of Catapres-TTS for lowering blood pressure.
 
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