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Taking Clonidine for ADHD and High Blood Pressure

Clonidine Tablet and Liquid Dosing for High Blood Pressure

For most people, the starting dosage for immediate-release clonidine tablets is 0.1 mg twice daily, taken at morning and bedtime. If necessary, your healthcare provider may slowly increase your dose. Your healthcare provider may recommend that you take a larger portion of the daily dose at bedtime (and a smaller portion in the morning), in order to reduce bothersome clonidine side effects like drowsiness or dry mouth. Elderly individuals and people with kidney disease may need a lower dosage.
For long-acting clonidine tablets or liquid (Nexiclon XR), the starting dosage for most people for high blood pressure treatment is clonidine ER 0.17 once daily at bedtime. This can be taken as one clonidine ER 0.17 mg tablet or as 2 mL of the clonidine ER liquid suspension. If necessary, your healthcare provider may slowly increase your dose. If you are switching from a different clonidine product, your healthcare provider will calculate an appropriate dosage based on your current clonidine dosage.
You should not abruptly stop taking clonidine, as serious problems (including a stroke or even death) may result. Your healthcare provider will advise you about how to safely stop taking this medication. It is usually recommended to slowly reduce the dose over at least two to four days, with careful monitoring. Let your healthcare provider know if you develop any problems while stopping clonidine.

Clonidine Dosing for ADHD

The usual starting dose of long-acting clonidine tablets (Kapvay) for attention deficit hyperactivity disorder (ADHD) treatment is 0.1 mg once daily at bedtime. Your child's healthcare provider may gradually increase the dose (only if necessary) as follows:
  • First week -- clonidine ER 0.1 mg at bedtime
  • Second week -- clonidine ER 0.1 mg in the morning and 0.1 mg at bedtime
  • Third week -- clonidine ER 0.1 mg in the morning and 0.2 mg at bedtime
  • Fourth week -- clonidine ER 0.2 mg in the morning and 0.2 mg at bedtime.
When stopping clonidine ER, it is usually recommended to gradually taper the dose down by 0.1 mg every three to seven days. Stopping clonidine ER abruptly might cause dangerously high blood pressure (hypertension), a rapid heart rate (tachycardia), and other symptoms.
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