Clonidine hydrochloride (Catapres^®, Catapres-TTS^®, Duraclon^®, Kapvay™, Nexiclon^® XR) is a prescription medicine approved for a few different uses, including high blood pressure, attention deficit hyperactivity disorder, and cancer pain. The drug works to decrease blood pressure by stimulating alpha-2 receptors in the brain stem. When used in an epidural to treat pain, it works by blocking pain signals from reaching the brain.

(Click Clonidine to learn more about the specific uses, potential side effects, and safety of this medication. You can also click on the various links in the box to the right to access specific topics on clonidine.)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD

Last reviewed by: Kristi Monson, PharmD

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