Specific Drugs That React With Demadex
Demadex should not be combined with aminoglycoside antibiotics unless absolutely necessary. Taking these two medications together can increase the chance of permanent hearing loss.
Other Blood Pressure Medicines
When taking Demadex with another high blood pressure medication, your blood pressure may decrease too much. In order to decrease the chances of this Demadex interaction, your healthcare provider may monitor you more closely and/or change the dose of either medicine.
Cholestyramine (Prevalite, Questran, Questran Light)
Cholestyramine may decrease the absorption of Demadex into the body, perhaps making it less effective. If you are taking both of these medications together, it is best to take them at different times of the day.
Taking Demadex with corticosteroids may increase your risk of low potassium levels (hypokalemia). Your healthcare provider should check your potassium levels and may need to take steps to correct your potassium levels.
Digoxin (Digitek, Lanoxin)
Demadex should be used carefully in people taking digoxin. Demadex can cause low potassium levels (hypokalemia), which can be especially dangerous for people taking digoxin.
Lithium (Eskalith, Lithobid)
Taking Demadex with lithium may increase the level of lithium in your blood, increasing your chance of side effects. In general, it is not usually recommended to take lithium with diuretics, including Demadex. Your healthcare provider may need to monitor your lithium level more closely and/or change your lithium dose.
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Taking Demadex with NSAIDs can make Demadex less effective and may increase your risk of side effects. Your healthcare provider may need to increase your dose of Demadex or may suggest an alternative to NSAIDs.