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How Demadex Works and Pediatric Use

Demadex for Water Retention
One common cause of water retention is congestive heart failure (CHF). Congestive heart failure is a condition where the heart cannot pump enough blood throughout the body. It does not mean that your heart has stopped or is about to stop working. It means that your heart is not able to pump blood the way that it should. This can lead to symptoms of CHF that include shortness of breath; swelling of the feet, ankles, or lower legs; and rapid weight gain (see Symptoms of Congestive Heart Failure for more information).
Demadex can help with water retention by helping the body to get rid of the extra fluid. Demadex does not cure congestive heart failure or other conditions that cause the body to retain fluid.
There are many other causes for fluid retention, including kidney failure (renal failure) and cirrhosis of the liver. Demadex can also be used to treat fluid retention due to these conditions.

How Does Demadex Work?

Demadex is a diuretic, which is commonly referred to as a "water pill." Specifically, Demadex is known as a "loop diuretic," named after the part of the kidneys it affects (the loop of Henle). It works by increasing the amount of salt and water the kidneys remove from the blood. This extra salt and water is passed out through the urine. By increasing the amount of water removed from the blood, Demadex causes a decrease in blood volume. Because of this effect, Demadex can lower blood pressure and can also help with water retention.

Demadex Use in Children

Demadex is not approved for use in children or adolescents, as it has not been adequately studied in these age groups. Talk to your child's healthcare provider about the benefits and risks of using Demadex in children.
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