Drug Interactions With Fosinopril-Hydrochlorothiazide

More Detail About Fosinopril-Hydrochlorothiazide Interactions

Diuretics
When taking fosinopril-hydrochlorothiazide with a diuretic, your blood pressure may decrease too much. This is more likely to occur when fosinopril-hydrochlorothiazide is first started. In order to decrease the chances of this interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of fosinopril-hydrochlorothiazide, and/or monitor you more closely.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
If you have kidney disease or kidney failure, taking both NSAIDs and fosinopril-hydrochlorothiazide may add to the damage that your kidneys are already experiencing. Also, NSAIDs may decrease the blood pressure-lowering effects of fosinopril-hydrochlorothiazide. For your particular situation, talk to your healthcare provider about using NSAIDs and fosinopril-hydrochlorothiazide together.
 
Potassium Supplements or Salt Substitutes With Potassium
If you are taking fosinopril-hydrochlorothiazide along with a potassium supplement or a salt substitute with potassium, the levels of potassium in your blood may become too high. This can cause serious problems. For your particular situation, talk to your healthcare provider about using potassium and fosinopril-hydrochlorothiazide together.
 
Potassium-Sparing Diuretics
If you are taking both fosinopril-hydrochlorothiazide and a potassium-sparing diuretic, your body may metabolize the drugs differently than intended and increase the levels of potassium in your blood. Your healthcare provider may choose to monitor your progress more closely.
 
Lithium (Eskalith, Lithane, Lithonate, Lithotabs)
If you are taking both fosinopril-hydrochlorothiazide and lithium, your body may metabolize the drugs differently than intended and increase the lithium levels in the blood. Your healthcare provider may choose to monitor your serum lithium levels more frequently.
(Drug Interactions With Fosinopril-Hydrochlorothiazide Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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