Furosemide Interactions Explained
Aminoglycoside Antibiotics
Furosemide should not be combined with aminoglycoside antibiotics unless absolutely necessary. Taking these two medications together can increase the chance of permanent hearing loss.
Other Blood Pressure Medicine
When taking furosemide with another
high blood pressure medication, your
blood pressure may decrease too much. In order to decrease the chances of this furosemide interaction, your healthcare provider may monitor you more closely and/or change the dose of either medicine.
Corticosteroids
Taking furosemide with corticosteroids may increase your risk of low potassium levels (hypokalemia). Your healthcare provider should check your potassium levels and may need to take steps to correct your potassium levels.
Digoxin (Digitek, Lanoxin)
Furosemide should be used carefully in people taking digoxin. Furosemide can cause low potassium levels (hypokalemia), which can be especially dangerous for people taking digoxin.
Ethacrynic Acid (Edecrin)
Furosemide should not be combined with
ethacrynic acid due to the risk of hearing loss.
Lithium (Eskalith, Lithobid)
Taking furosemide with
lithium may increase the level of lithium in your blood, increasing your chance of side effects. In general, it is usually not recommended to combine lithium with diuretics, including furosemide. Your healthcare provider may need to monitor your lithium level more closely and/or change your lithium dose.
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Taking furosemide with
NSAIDs can make furosemide less effective and may increase your risk of side effects. Your healthcare provider may need to increase your dose of furosemide or may suggest an alternative to NSAIDs.
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