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What Are the Substitutes for HCTZ?

HCTZ Alternatives for Water Retention

There are other alternatives to HCTZ when treating fluid retention (edema), including:
  • Limiting your salt and fluid intake
  • Wearing support stockings to reduce fluid retention in the legs
  • Becoming more active (avoiding sitting or standing in the same position for too long)
  • Taking other diuretic medications, such as:
o Eplerenone (Inspra®)
o Triamterene (Dyrenium®)
o Bumetanide (Burinex®)

HCTZ Alternatives: A Summary

There are several alternatives to HCTZ, including other medications or lifestyle changes. If HCTZ is not working for you or if it is causing bothersome side effects, ask your healthcare provider about trying a HCTZ alternative.
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