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General Instructions for Taking HCTZ

General HCTZ Dosage Information

Some considerations for people taking HCTZ include:
  • HCTZ comes in tablet and capsule form. It is usually taken by mouth once a day, although it may be taken several times a day.
  • It does not matter if you take HCTZ with or without food.
  • If necessary, HCTZ tablets (but not capsules) may be split in half.
  • HCTZ should be taken at the same time each day to maintain an even level of HCTZ in your blood. However, some people do not need to take HCTZ every day, especially people taking it for fluid retention.
  • Because HCTZ increases urination, it is best to take it in the morning (to avoid needing to get up to use the bathroom throughout the night). If you take HCTZ multiple times per day, it is best to take the last dose of the day before 6 PM (unless you are instructed otherwise).
  • For HCTZ to work properly, you have to take it as prescribed; it will not work if you stop taking it.
  • If you are unsure about anything related to HCTZ or your HCTZ dosage, please talk to your doctor, nurse, or pharmacist.
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