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Effects of HCTZ for Water Retention and Specific Uses

HCTZ for Water Retention
One common cause of water retention is congestive heart failure (CHF). Congestive heart failure is a condition where the heart cannot pump enough blood throughout the body. It does not mean that your heart has stopped or is about to stop working. It means that your heart is not able to pump blood the way that it should. This can lead to symptoms of CHF that include: shortness of breath; swelling of the feet, ankles, or lower legs; and rapid weight gain (see Symptoms of Congestive Heart Failure for more information).
There are many other causes for fluid retention, including kidney failure (renal failure), cirrhosis, estrogens, and corticosteroids.
HCTZ can help with water retention by helping the body get rid of the extra fluid. HCTZ is approved to treat water retention (edema) when used along with other medications, including other congestive heart failure medications. HCTZ does not cure congestive heart failure or other conditions that cause the body to retain fluid.

How Does HCTZ Work?

HCTZ is a diuretic, which is commonly referred to as a "water pill." It works by increasing the amount of salt and water that the kidneys remove from the blood. This extra salt and water is passed out through the urine. By increasing the amount of water removed from the blood, HCTZ causes a decrease in blood volume, which can lower blood pressure. By removing extra water from the body, HCTZ also helps decrease swelling and water retention.

HCTZ Uses in Children

HCTZ has been approved for use in children and infants.

Off-Label HCTZ Uses

On occasion, your healthcare provider may recommend HCTZ for treating a condition other than those listed above. This is called an "off-label" use. At this time, there are a few off-label uses of HCTZ, including:
  • Treatment of certain types of diabetes insipidus (a problems with the kidneys)
  • Treatment of water retention due to premenstrual syndrome (PMS).
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HCTZ Diuretic

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