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Precautions and Warnings With HCTZ

Being aware of the precautions and warnings with HCTZ before starting the medication can help eliminate risks and help ensure a safe treatment process. Certain people should not take HCTZ, including those who are allergic to sulfonamide-derived drugs, are not producing any urine, or are allergic to any components used to make HCTZ. There are also a number of potential side effects that may occur with the medicine, including allergic reactions and increased blood sugar levels.

HCTZ: What Should I Tell My Healthcare Provider?

Prior to taking HCTZ (hydrochlorothiazide or HCT), you should talk with your healthcare provider if you have:
 
  • Liver disease, including cirrhosis
  • Kidney disease or kidney failure
  • Diabetes
  • Systemic lupus erythematosus (lupus or SLE)
  • A personal or family history of angioedema, which is swelling under the skin
  • Gout
  • Pancreatitis
  • High cholesterol
  • Allergies
  • Asthma
  • Fluid or electrolyte problems
  • Parathyroid problems
  • Had a sympathectomy (a specific kind of surgery)
  • Any allergies, including allergies to HCTZ, ACE inhibitors, sulfa drugs, foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you:
 
Tell your healthcare provider about all other medicines you may currently be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
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