As the name implies, spironolactone-HCTZ contains two medications: spironolactone and hydrochlorothiazide (HCTZ). This combination diuretic is sold under the brand name Aldactazide® and is approved for the following uses:
- Controlling high blood pressure (hypertension)
- Treating water retention (edema) caused by the following conditions:
Spironolactone-HCTZ comes in tablet form and is taken once or twice a day. Because this drug has been shown to cause tumors in animal studies, it should only be used when other treatments have failed or have not been adequate.
(For more information on this medicine, click Spironolactone. This article tells you what you need to know about potential side effects, dosing guidelines, available strengths, and more.)