Indapamide and Pregnancy
Animal studies on indapamide and pregnancy show that the medication does not appear to cause harm to a developing fetus. Since animals do not always respond to drugs the same way that humans do, however, the full risks to a human fetus are not known. If you are taking indapamide and pregnancy occurs, your healthcare provider will weigh the benefits and risks before making a recommendation.
Indapamide (Lozol®) is a pregnancy Category B medicine, meaning that it is probably safe for use during pregnancy, although the full risks are not known.
The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category B is given to medicines that have not been studied in pregnant humans but do not appear to cause harm to the fetus in animal studies.
However, it is important to note that animals do not always respond to medicines the same way that humans do. Therefore, the full risks to a fetus are not known, and a pregnancy Category B medicine should be given to a pregnant woman only if the healthcare provider believes that the benefits to the pregnant woman outweigh any possible risks to the unborn child. In general, diuretics (including indapamide) should not be used to treat high blood pressure during pregnancy (gestational hypertension).
If you are pregnant or thinking of becoming pregnant while taking indapamide, let your healthcare provider know. He or she will consider both the benefits and risks of indapamide during pregnancy before making a recommendation for your particular situation.