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Side Effects of Indapamide
Some of the most common side effects of indapamide include fatigue, back pain, and muscle cramps or spasms. In most cases, side effects of the drug are minor and don't require medical attention. There are, however, a number of potentially serious indapamide side effects that should be reported to a healthcare provider immediately, including lightheadedness, high blood sugar, or signs of dehydration.
As with any medicine, there are possible side effects with indapamide (Lozol®); however, not everyone who takes the medicine will experience side effects. In fact, most people tolerate indapamide well. When side effects do occur, in most cases they are minor and either require no treatment or can be easily treated by you or your healthcare provider.
(The side effects discussed below are not a complete list of side effects reported with indapamide. Your healthcare provider can discuss a more complete list of indapamide side effects with you.)
Indapamide has been studied thoroughly in clinical trials in which a group of people taking the drug have side effects documented and compared to another group not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
In these studies, the most common indapamide side effects (occurring in at least 5 percent of people) included:
- Headache
- Infections
- Back pain
- Dizziness
- Irritated or runny nose
- Fatigue or weakness
- Muscle cramps or muscle spasm
- Nervousness, anxiety, or tension.
Other common side effects, occurring in between 1 and 5 percent of people, included (but are not limited to):
- Flu-like symptoms (such as fever or chills)
- Abdominal pain (stomach pain) or nausea
- Chest pain
- Constipation or diarrhea
- Indigestion
- Dry mouth (see Indapamide and Dry Mouth)
- Coughing
- Sinus infection or irritation
- Sore throat
- Conjunctivitis ("pink eye")
- Lightheadedness
- Vertigo (a sense of spinning)
- Depression (see Indapamide and Depression)
- Insomnia or drowsiness
- Blurred vision
- Impotence, also known as erectile dysfunction or ED (see Indapamide and Impotence).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



