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Important Safety Concerns With Isoptin SR

Specific Isoptin SR Warnings and Precautions

Warnings and precautions to be aware of prior to taking Isoptin SR include the following:
  • Isoptin SR can slow down the heart rate. This can be a problem in people who have certain types of arrhythmias or people taking other medications that can slow down the heart rate.
  • The medication should be used with caution in people who have congestive heart failure (CHF). Isoptin SR can cause fluid retention (edema) and can decrease the heart's ability to pump blood, which can be especially dangerous in people with CHF.
  • If the left side of your heart is weak (called left ventricular dysfunction), you are at risk for heart failure and should use Isoptin SR with caution. Isoptin SR should not be combined with beta blockers in people who have this condition.
  • Isoptin SR can lower your blood pressure. Be sure to let your healthcare provider know if you have signs of low blood pressure, including dizziness, lightheadedness, or fainting.
  • The medication can increase liver enzymes (diagnosed using a blood test), which may be a sign of liver damage.
  • Isoptin SR can affect the electrical system of the heart, causing "heart block." This happens when signals from one part of the heart have trouble reaching the other parts. If this happens to you, your healthcare provider should lower your Isoptin SR dosage or take you off the medication altogether.
  • Isoptin SR is metabolized and removed from the body using the liver and kidneys. If you have liver or kidney disease, the drug may accumulate in your body. Your healthcare provider should monitor you more closely and may need to decrease your dosage.
  • The medication can interrupt nerve signals to the muscles in people who have Duchenne's muscular dystrophy or myasthenia gravis.
  • Isoptin SR can interact with a number of medicines (see Isoptin SR Drug Interactions).
  • Isoptin SR is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy. Talk to your healthcare provider about the risks and benefits of using the drug while pregnant (see Verapamil and Pregnancy).
  • Isoptin SR does pass through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to using the drug (see Verapamil and Breastfeeding).
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Isoptin SR Information

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