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Safety Concerns With Kerlone

Specific Kerlone Warnings and Precautions

Some warnings and precautions to be aware of prior to taking this medication include the following:
  • Beta blockers can worsen breathing problems like asthma or COPD. If you have breathing problems, check with your healthcare provider before taking Kerlone. Even though Kerlone is a "cardioselective" beta blocker (meaning it is more likely to affect the heart and blood vessels than the lungs), it can still cause problems for people with asthma or COPD.
  • As with all beta blockers, you should not abruptly stop taking Kerlone, as serious problems (including heart attacks) may result. Your healthcare provider will advise you about how to safely stop taking this medication. It is usually recommended to slowly reduce the dose over a period of one to two weeks, with careful monitoring, and to minimize physical activity during this time. Let your healthcare provider know if you develop chest pain or any other problems while stopping Kerlone.
  • The kidneys help remove Kerlone from the body. If you have kidney disease, your healthcare provider may need to monitor your response to Kerlone more closely (and a lower Kerlone dosage may be recommended).
  • Like all beta blockers, Kerlone can worsen heart failure in some situations. However, beta blockers are also useful for the treatment of heart failure. If you have heart failure, your healthcare provider may need to monitor you very closely while you take Kerlone. Let your healthcare provider know immediately if your heart failure symptoms seem to worsen.
  • If you will be having surgery, make sure your surgeon and anesthesiologist know you take Kerlone, as it may affect the choice of medications used during the surgery.
  • Beta blockers can mask some of the symptoms of low blood sugar (hypoglycemia), particularly the "racing heart" feeling. This can cause serious problems for people with diabetes, who need to be able to sense that they have low blood sugar (in order to correct it before it becomes life-threatening).
  • Beta blockers can mask some of the symptoms of an overactive thyroid (hyperthyroidism). Stopping Kerlone suddenly could cause symptoms of a "thyroid storm" (a sudden and severe worsening of hyperthyroidism symptoms).


  • Kerlone could potentially worsen psoriasis; this must be considered before this medication is used by people with psoriasis.
  • Kerlone should not be used in people with untreated pheochromocytoma.
  • Like other beta blockers, Kerlone may be associated with the development of lupus. 


  • Kerlone can potentially interact with many other medications (see Kerlone Interactions).
  • If you have an anaphylactic allergy (the type that affects the entire body and often interferes with breathing), Kerlone may make you more sensitive to the allergen and may make the usual treatments (such as epinephrine or an EpiPen®) less effective.
  • Kerlone is considered a pregnancy Category C medication. This means that it might not be safe during pregnancy, although the full risks are not currently known (see Betaxolol and Pregnancy).
  • Kerlone passes through breast milk in humans. Therefore, if you are breastfeeding or plan to start breastfeeding, discuss this with your healthcare provider prior to taking the drug (see Betaxolol and Breastfeeding).
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