Drug Interactions With Lisinopril-Hydrochlorothiazide

Gold
If you are on liquid gold therapy, there is a possibility that lisinopril-hydrochlorothiazide will interact with the liquid gold. Symptoms of such an interaction may include facial flushing, nausea, vomiting, and low blood pressure. Contact your healthcare provider if you experience any of these symptoms.
 
Insulin
Taking insulin with lisinopril-hydrochlorothiazide may cause high blood sugar (hyperglycemia). For your particular situation, your healthcare provider may monitor you more closely and adjust your dose of insulin as needed.
 
Oral Diabetes Medication
Taking an oral diabetes medication with lisinopril-hydrochlorothiazide may increase blood sugar levels. For your particular situation, your healthcare provider may monitor you more closely and adjust your dose of diabetes medications as needed.
 
Other Blood Pressure Medicine
When taking lisinopril-hydrochlorothiazide with another high blood pressure medication, your blood pressure may decrease too much. In order to decrease the chances of developing this lisinopril-hydrochlorothiazide interaction, your healthcare provider may monitor you more closely, change the dose of either medicine, or both.
 
Alcohol
When taking lisinopril-hydrochlorothiazide with alcohol, your blood pressure may decrease too much. For your particular situation, make sure to talk with your healthcare provider about drinking alcohol while taking lisinopril-hydrochlorothiazide.
 
Barbiturates (Amytal, Butisol Sodium, Luminal, Mysoline, Nembutal, Pentothal)
When taking lisinopril-hydrochlorothiazide with a barbiturate, your blood pressure may decrease too much. In order to reduce your chances of experiencing this lisinopril-hydrochlorothiazide interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of lisinopril-hydrochlorothiazide, and monitor you more closely.
(Drug Interactions With Lisinopril-Hydrochlorothiazide Continued: Page 4)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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