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Other Drugs That Can React With Lisinopril-Hydrochlorothiazide

Alcohol
When taking lisinopril-hydrochlorothiazide with alcohol, your blood pressure may decrease too much. For your particular situation, make sure to talk with your healthcare provider about drinking alcohol while taking lisinopril-hydrochlorothiazide.
 
Barbiturates (Amytal, Butisol Sodium, Luminal, Mysoline, Nembutal, Pentothal)
When taking lisinopril-hydrochlorothiazide with a barbiturate, your blood pressure may decrease too much. In order to reduce your chances of experiencing this lisinopril-hydrochlorothiazide interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of lisinopril-hydrochlorothiazide, and monitor you more closely.
 
Narcotics
When taking lisinopril-hydrochlorothiazide with a narcotic, your blood pressure may decrease too much. To decrease your chances of having such an interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of lisinopril-hydrochlorothiazide, and monitor you more closely.
 
Cholestyramine (Prevalite, Questran, Questran Light, LoCholest)
Cholestyramine can bind to lisinopril-hydrochlorothiazide in the digestive tract and decrease its absorption into the body. To avoid this drug interaction, take lisinopril-hydrochlorothiazide at least one hour before or four to six hours after taking cholestyramine.
 
Colestipol (Colestid)
Colestipol can bind to lisinopril-hydrochlorothiazide in the digestive tract and decrease its absorption into the body. Therefore, take lisinopril-hydrochlorothiazide at least one hour before or four to six hours after taking colestipol to avoid this drug interaction.
 
Corticosteroids (Hexadrol, Cortef, Decadron)
Taking corticosteroids with lisinopril-hydrochlorothiazide may cause an electrolyte imbalance, especially with the levels of potassium in the blood. If you are taking a corticosteroid with lisinopril-hydrochlorothiazide, your healthcare provider may monitor you more closely and adjust your dose of medicine as needed.
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