Aliskiren/amlodipine is a drug prescribed for the treatment of high blood pressure. The two components work together to reduce the rate at which calcium moves into the blood vessel walls and inhibit the action of an enzyme that has an effect on blood pressure. It is typically taken once a day. The most commonly reported side effect is water retention.
As with any medicine, side effects are possible with aliskiren/amlodipine. However, not everyone who takes the drug will experience problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious reactions are less common.
The most common side effect seen with aliskiren/amlodipine is swelling (water retention) in the lower limbs.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Tekamlo [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation;2011 October.
Food and Drug Administration, Center for Drug Evaluation and Research. FDA drug safety communication: new warning and contraindication for blood pressure medicines containing aliskiren (Tekturna) (4/20/2012). FDA Web site. Available at: http://www.fda.gov/Drugs/DrugSafety/ucm300889.htm. Accessed April 25, 2012.
Tekturna [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation;2011 February.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed September 14, 2010.
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