Hypertension Home > Understanding the Effects of Aliskiren Treatment

Effects of Aliskiren

A blood pressure reading consists of two numbers -- for example, 120/80. The top number is the systolic blood pressure, and the bottom number is the diastolic blood pressure. Studies have shown that aliskiren lowers systolic and diastolic blood pressures when used alone or in combination with other blood pressure medications. In studies where aliskiren was used alone for the treatment of mild to moderate high blood pressure, it lowered systolic blood pressure by up to 11.2 mm Hg on average and lowered diastolic blood pressure by up to 7.5 mm Hg on average, compared to a placebo (a "sugar pill" that does not contain any active ingredients).
Studies have also shown that a combination of aliskiren with hydrochlorothiazide (a diuretic) or with valsartan (an ARB blood pressure medication) can further reduce blood pressure, compared with any of the medications used alone.

When and How to Take Aliskiren

General considerations for when and how to take this drug include the following:
  • The medication comes in tablet form. It is taken by mouth once daily.
  • You should take aliskiren consistently, either with or without food (fatty meals may decrease the absorption of the drug). Whether you take it with food or not does not matter, as long as you are consistent (in other words, either always take it with food or never take it with food).
  • Make sure to take aliskiren at the same time each day to maintain an even level of in your blood.
  • For the medication to work properly, it must be taken as prescribed. It will not work if you stop taking it.

Who Makes It?

Aliskiren is made by Novartis Pharmaceuticals Corporation.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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