Amlodipine and valsartan is a combination medicine that is used for the treatment of high blood pressure. By relaxing the blood vessels, the medication improves blood flow and helps to lower blood pressure. Amlodipine and valsartan is available by prescription and comes in tablet form. While most people tolerate the drug well, possible side effects include water retention, dizziness, and sore throat.
Amlodipine and valsartan is made by Novartis Pharmaceuticals.
How Does Amlodipine and Valsartan Work?
Amlodipine and valsartan contains two medications, amlodipine and valsartan. Amlodipine is a calcium channel blocker. It helps to slow down the rate at which calcium moves into the walls of the blood vessels. This, in turn, helps to relax the blood vessels, which improves blood flow and lowers blood pressure.
Valsartan belongs to a class of drugs called angiotensin II receptor blockers. Angiotensin II is a naturally occurring chemical in the body that causes blood vessels to narrow (constrict). By blocking angiotensin II, valsartan helps to relax the blood vessels, lowering blood pressure.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Exforge [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation;2012 November.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed July 18, 2007.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed July 18, 2007.
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