Hypertension Home > Precautions and Warnings With Azilsartan
If your healthcare provider prescribes azilsartan to treat high blood pressure, make sure he or she is aware of any other medical conditions you have and any other medications you are taking. Some precautions with azilsartan include potential warnings of drug interactions, allergic reactions, and an increased risk for problems such as high blood potassium levels or angioedema.
What Should I Tell My Healthcare Provider?Talk with your healthcare provider prior to taking azilsartan medoxomil (Edarbi™) if you have:
- Heart disease, including congestive heart failure (CHF)
- Kidney disease, such as kidney failure (renal failure)
- A history of high blood potassium (hyperkalemia) or have to use salt substitutes
- A personal or family history of angioedema, which is swelling beneath the skin
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Specific Azilsartan Precautions and WarningsSome warnings and precautions to be aware of prior to taking this medicine include the following:
- Medications similar to azilsartan can cause a potentially dangerous swelling below the surface of the skin, called angioedema, especially within the first month of treatment. Although this has not specifically been reported with azilsartan, it is still a good idea to watch for this problem. Stop taking azilsartan and seek immediate medical care if you develop any symptoms of angioedema, such as difficulty breathing or swelling of the face, eyes, lips, tongue, hands, or feet.
- You may experience dizziness or lightheadedness when you first start taking azilsartan as your blood pressure begins to lower. If you find yourself fainting, stop taking this drug and contact your healthcare provider as soon as possible.
- Sweating, dehydration (which could occur if you do not drink enough fluids), vomiting, and diarrhea could cause your blood pressure to lower to unsafe levels while taking azilsartan. Stay hydrated by drinking plenty of fluids, and let your healthcare provider know if you develop these symptoms.
- You should not use potassium supplements or salt substitutes that contain potassium without first checking with your healthcare provider. Azilsartan may cause an increase in blood potassium levels (hyperkalemia), and taking products that contain potassium may further increase the level of potassium in your blood. People who have kidney disease or diabetes also have an increased risk for hyperkalemia with this medicine.
- If you are having any major surgery, make sure your healthcare provider knows you are taking azilsartan.
- Azilsartan may cause a decrease in kidney function, especially in people who have kidney disease or severe congestive heart failure (CHF). Your healthcare provider may choose to monitor your kidney function with a blood test while you are taking it. Contact your healthcare provider if you notice a decrease in urination or swelling in your hands, legs, ankles, or feet, which can be signs of kidney problems.
- Azilsartan can potentially react with a number of other medications (see Drug Interactions With Azilsartan).
- Azilsartan is a pregnancy Category D medication for all three trimesters. This means that it may cause harm to an unborn child (see Edarbi and Pregnancy).
- It is not known whether azilsartan passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking this medication (see Edarbi and Breastfeeding).