Benazepril has been licensed to treat high blood pressure. The medication causes blood vessels to relax, which can help lower blood pressure. In clinical studies, benazepril reduced systolic blood pressure by 6 to 12 mmHg and diastolic blood pressure by 4 to 7 mmHg. The most common side effects include headache, dizziness, and fatigue.
Benazepril is manufactured by Novartis Pharmaceuticals.
How Does It Work?
The medication is part of a class of drugs called ACE inhibitors. ACE stands for angiotensin-converting enzyme. Benazepril helps to block this enzyme, which is normally part of a reaction in the body that causes the blood vessels to narrow (constrict). By blocking this enzyme, the medication causes blood vessels to relax, which can lower blood pressure.
Effects of Benazepril
A blood pressure reading consists of two numbers -- for example: 120/80. The top number is known as the systolic blood pressure and the bottom number is the diastolic blood pressure. During clinical studies in people taking benazepril, systolic blood pressure decreased, on average, by 6 to 12 mmHg and diastolic blood pressure decreased by 4 to 7 mmHg, on average. The higher the dose, the greater the drop in blood pressure tended to be.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Lotensin [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation;2012 September.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/.
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