Dynacirc is a prescription drug that is licensed for the treatment of high blood pressure. It is a type of calcium channel blocker, which works by relaxing the blood vessels to allow better blood flow and to make it easier for the heart to pump blood. Dynacirc comes in capsule form and is generally taken twice daily. Potential side effects include nausea, flushing, and fatigue.
Brand-name Dynacirc was made by Reliant Pharmaceuticals, although it is no longer being manufactured. Generic Dynacirc is still available and is made by Abrika Pharmaceuticals and Actavis.
How Does It Work?
Dynacirc is part of a class of drugs called calcium channel blockers. It helps slow down the rate at which calcium moves into your heart and blood vessel walls. This, in turn, helps to relax the vessels, which allows better blood flow and makes it easier for the heart to pump blood.
There are two basic types of calcium channel blockers: dihydropyridine and non-dihydropyridine. The most important difference between the two is that non-dihydropyridine calcium channel blockers can slow down the heart rate, while dihydropyridine calcium channel blockers do not. Dynacirc is a dihydropyridine calcium channel blocker, which means that it does not usually decrease the heart rate.
In clinical studies, Dynacirc was shown to decrease blood pressure within two to three hours of the first dose. The effects of a single dose lasted about 12 hours. These studies also showed that Dynacirc slightly increased the heart rate (by about three to five beats per minute).
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Dynacirc [package insert]. Liberty Corner, NJ: Reliant Pharmaceuticals;2006 May.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed March 20, 2007.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed March 20, 2007.
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