Hypertension Home > Specific Safety Concerns With Moexipril

Specific Moexipril Precautions and Warnings

Some warnings and precautions to be aware of prior to taking this drug include the following:
  • Moexipril can cause a potentially dangerous swelling below the surface of the skin, called angioedema, especially within the first month of treatment. If you develop any symptoms of angioedema, such as swelling of the face, eyes, lips, tongue, hands, or feet or difficulty breathing, stop taking moexipril and seek immediate medical care.
  • Moexipril may cause a swelling in the intestines known as intestinal angioedema. The most common symptom of this problem is stomach pain. Contact your healthcare provider if you experience stomach pain while taking moexipril.
  • You may experience dizziness or lightheadedness when you first start using moexipril as your blood pressure starts to lower. If you find yourself fainting, stop taking this drug and contact your healthcare provider as soon as possible.
  • Sweating, dehydration (which could occur if you do not drink enough fluids), vomiting, and diarrhea could cause your blood pressure to lower too much while taking moexipril. Stay hydrated by drinking plenty of fluids, and let your healthcare provider know if you develop these conditions.
  • You should not use potassium supplements, or salt substitutes that contain potassium, without first checking with your healthcare provider. Moexipril may cause an increase in blood potassium levels (hyperkalemia), and taking products that contain potassium may further increase the level of potassium in your blood. People who have kidney disease or diabetes also have an increased risk for hyperkalemia from moexipril.
  • This medication may cause a drop in white blood cells, which could increase your risk for developing an infection. People with kidney disease may have an increased risk for this side effect. Contact your healthcare provider if you develop signs of an infection, such as a fever or sore throat.
  • If you are having any major surgery, make sure your healthcare provider knows you are taking moexipril.
  • There have been reports of life-threatening allergic reactions occurring in certain people taking medications like moexipril, including people undergoing kidney dialysis and people receiving bee or wasp venom to protect against sting allergies.
  • In rare cases, ACE inhibitors have potentially caused liver failure. If you develop any signs of liver problems, including tiredness or fatigue, dark urine, pain in the right upper part of the stomach, or yellowing of the whites of the eyes or skin (jaundice), contact your healthcare provider immediately.
  • This medication may cause a decrease in kidney function, especially in people who are elderly, have kidney disease, have severe congestive heart failure (CHF), or are taking nonsteroidal anti-inflammatory drugs (NSAIDs) or diuretics (water pills). Your healthcare provider may choose to monitor your kidney function with a blood test while you are taking it. Contact your healthcare provider if you notice a decrease in urination or swelling in your hands, legs, ankles, or feet, which can be signs of kidney problems.


  • All ACE inhibitors are known to cause a persistent, nonproductive cough (see Univasc Cough). If you develop a bothersome cough while taking moexipril, talk to your healthcare provider. Your healthcare provider may be able to switch you to a medication that does not cause a cough.
  • Moexipril can potentially react with a number of other medications (see Drug Interactions With Moexipril).
  • Moexipril is considered a pregnancy Category C medication in the first trimester and a Category D medication in the second and third trimesters. This means that it may cause harm to an unborn child (see Univasc and Pregnancy).
  • It is not known whether Moexipril passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking this medication (see Univasc and Breastfeeding).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation




Related Channels

eMedTV Links
Copyright © 2006-2018 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.