Nisoldipine is commonly used in the treatment of high blood pressure. It helps to relax blood vessels, which allows for better blood flow and makes it easier for the heart to pump blood. Nisoldipine, which is available by prescription, comes in the form of extended-release tablets and is usually taken once a day. Possible side effects include sore throat, dizziness, headache, and water retention.
Nisoldipine is part of a class of drugs called calcium channel blockers. The drug helps slow down the rate at which calcium moves into your heart and into the blood vessel walls. This, in turn, helps to relax the vessels, which allows for better blood flow and makes it easier for the heart to pump blood.
There are two basic types of calcium channel blockers: dihydropyridine and non-dihydropyridine. The most important difference between the two types is that non-dihydropyridine calcium channel blockers can slow down the heart rate, while dihydropyridine calcium channel blockers do not. Nisoldipine is a dihydropyridine calcium channel blocker, which means that it does not usually decrease the heart rate.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed February 3, 2011.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
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