Hypertension Home > Products That May React With Olmesartan Medoxomil/Amlodipine/Hydrochlorothiazide
More Detail on Drug Interactions With Olmesartan Medoxomil/Amlodipine/HydrochlorothiazideThe following sections explain in detail the potentially negative reactions that can occur when olmesartan medoxomil/amlodipine/hydrochlorothiazide is combined with any of the drugs listed above.
Taking an ACE inhibitor with olmesartan medoxomil/amlodipine/hydrochlorothiazide may increase your risk for severely low blood pressure (hypotension), high blood potassium (hyperkalemia), or kidney problems. If you take these medications together, your healthcare provider should closely monitor your blood pressure, potassium levels, and kidney function.
Drinking alcohol with olmesartan medoxomil/amlodipine/hydrochlorothiazide may cause your blood pressure to decrease too much. If you consume alcohol while taking this medication, watch for symptoms of low blood pressure, such as dizziness, lightheadedness, or fainting. If you experience any of these symptoms, contact your healthcare provider.
Angiotensin II Receptor Blockers (ARBs)
Olmesartan medoxomil/amlodipine/hydrochlorothiazide contains an ARB (olmesartan) and should generally not be combined with other ARBs, as this could increase the risk for high blood potassium or other side effects, such as kidney problems and very low blood pressure.
Taking a barbiturate with olmesartan medoxomil/amlodipine/hydrochlorothiazide may cause your blood pressure to decrease too much. If you take these medications together, your healthcare provider may need to monitor you more closely or lower your olmesartan medoxomil/amlodipine/hydrochlorothiazide dose.
Bile Acid Sequestrant Cholesterol Medications
Bile acid sequestrant medications can bind to olmesartan medoxomil/amlodipine/hydrochlorothiazide in the gastrointestinal tract and decrease the amount of olmesartan medoxomil/amlodipine/hydrochlorothiazide absorbed into the body. To help minimize this reaction, take olmesartan medoxomil/amlodipine/hydrochlorothiazide at least one hour before or four to six hours after a bile acid sequestrant.