Hypertension Home > Plendil Warnings and Precautions

Reviewing Plendil warnings and precautions with your healthcare provider prior to beginning treatment can help minimize risks and potentially dangerous interactions. For example, tell your healthcare provider if you have certain health conditions, such as congestive heart failure or liver disease. Plendil warnings and precautions also extend to people who have certain allergies and women who are pregnant or breastfeeding.

Plendil: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Plendil® (felodipine) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Plendil Warnings and Precautions

Warnings and precautions to be aware of prior to taking Plendil include the following:
  • In general, people who have congestive heart failure (CHF) should not use calcium channel blockers (including Plendil). These medications can cause water retention (edema), which can be especially dangerous for people with heart failure.
  • If you have liver disease or liver failure, your body may not metabolize Plendil as well as it should. Therefore, you may require extra monitoring by your healthcare provider, and you may need to take a lower Plendil dosage.
  • Plendil can interact with a number of medicines (see Plendil Drug Interactions).
  • The most common side effect of Plendil is water retention or swelling in the lower legs, hands, or feet. While this is not usually dangerous, it is important to let your healthcare provider know if you are experiencing severe swelling or rapid weight gain while taking the drug.
  • Plendil is considered a pregnancy Category C medication. This means that it may not be safe to use during pregnancy. Talk to your healthcare provider about the risks and benefits of using the drug when pregnant (see Felodipine and Pregnancy).
  • It is not known if Plendil passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Felodipine and Breastfeeding).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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