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Clinical studies of Procardia XL and depression have shown that less than 1 percent of people taking the medication had symptoms of depression. However, because depression is so common within the general population, it is difficult to determine whether Procardia XL alone actually causes depression or if it is a combination of factors. If you develop symptoms of depression while taking Procardia XL, be sure to discuss this with your healthcare provider.

Procardia XL and Depression: An Overview

Procardia XL® (nifedipine) is a prescription medication known as a calcium channel blocker. It is used to treat chest pain (known medically as angina) and high blood pressure (hypertension).
 
Just like with any other medicine, there are potential side effects with Procardia XL. One of these possible side effects is depression.
 

Procardia XL and Depression: How Common Is It?

The safety and effectiveness of Procardia XL has been studied in many people. In these clinical trials, less than 1 percent of people reported depression as one of the Procardia XL side effects.
 
The challenge with Procardia XL and depression is that, given how rarely depression is reported with Procardia XL and how common it is within the general population, it is difficult to tell whether depression is caused by Procardia XL alone, other factors, or a combination of both.
 

Procardia XL and Depression: Suggestions

For people taking Procardia XL, depression may occur. Therefore, if you notice any possible symptoms of depression while taking Procardia XL, or something "just does not seem right," you should talk to your healthcare provider. Your healthcare provider will be able to diagnose and treat the problem. If your healthcare provider believes the medicine may be causing your symptoms, he or she may recommend another angina or blood pressure medicine.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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