Hypertension Home > What Is Propranolol/HCTZ Used For?

Adults who have high blood pressure may benefit from propranolol/HCTZ. By increasing the amount of water and salt removed from the blood and reducing the workload on the heart, this combination medication causes a decrease in blood volume and makes it easier for the heart to pump blood. Propranolol/HCTZ can be used off-label as the first medication in people beginning high blood pressure treatment.

An Overview of Uses for Propranolol/HCTZ

Propranolol/HCTZ (Inderide®) is a combination prescription medication approved to lower blood pressure in people with hypertension (high blood pressure). It combines two high blood pressure drugs: propranolol (Inderal®) and hydrochlorothiazide (Microzide®, Oretic®), or HCTZ for short.
Propranolol/HCTZ may be a good option for people who are already taking propranolol or HCTZ but need another medication to control their blood pressure. It may also make sense for people who are already taking propranolol and HCTZ as two separate pills and want to take one pill instead of two. Propranolol/HCTZ is not approved for use as the first medication in people who have high blood pressure.

Propranolol/HCTZ Use for High Blood Pressure

Blood pressure is a measure of the force inside your blood vessels -- both while the heart is beating and while it is relaxed. High blood pressure, known medically as hypertension, is when that force is too high. When you have high blood pressure, your heart has to work harder to pump blood through your body.
Blood pressure measurements are reported in millimeters of mercury (mmHg), and are given as two numbers. The top number, or the systolic pressure, is a measure of blood pressure when the heart is beating. The bottom number, or the diastolic pressure, is a measure of blood pressure when the heart is relaxed.
High blood pressure is usually defined as an average blood pressure higher than 140/90, over multiple blood pressure readings. However, in some cases, your healthcare provide may consider a lower blood pressure reading to be too high, which might be the case if you have certain medical conditions such as diabetes.
Most people with high blood pressure will not experience any symptoms. However, over time, high blood pressure can damage many of the body's vital organs, including the eyes, heart, brain, and kidneys. Because of this damage, untreated hypertension may lead to serious health problems, such as:
(Click Effects of High Blood Pressure for more information.)
Although propranolol/HCTZ lowers blood pressure, it is not a cure for high blood pressure. If you stop taking this medication, it is likely that your blood pressure will increase. Most people with this condition need to take medication their entire lives.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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