Hypertension Home > Side Effects of Trandolapril-Verapamil ER

Like any medication, trandolapril-verapamil ER has some potential side effects. A few common side effects of trandolapril-verapamil ER include constipation, increased liver enzymes in the blood, and a cough. There are also some trandolapril-verapamil ER side effects that you should report immediately to your healthcare provider, such as difficulty breathing or swallowing, unexplained blisters or peeling of the skin, and unexplained weight gain. Some rare side effects of this medicine include insomnia, dry mouth, and erectile dysfunction.

Side Effects of Trandolapril-Verapamil ER -- An Overview

As with any medicine, there are possible side effects associated with trandolapril-verapamil hydrochloride ER (Tarka®). However, not everyone who takes trandolapril-verapamil ER will experience side effects. In fact, most people tolerate trandolapril-verapamil ER well. When people do develop trandolapril-verapamil ER side effects, in many cases they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider. Serious side effects can occur, but are less common.
(The trandolapril-verapamil ER side effects discussed below are not a complete list of side effects reported with trandolapril-verapamil ER. Your healthcare provider can discuss a more complete list of side effects with you.)

Common Side Effects of Trandolapril-Verapamil ER

Trandolapril-verapamil ER has been studied extensively in clinical trials, with thousands of people worldwide having been evaluated. In these studies, side effects are always documented and compared to side effects that occur in a similar group of people not taking the medicine. Based on these studies, the most common trandolapril-verapamil ER side effects seen in people with high blood pressure include:
  • Headaches -- up to 8.9 percent of people
  • Upper respiratory tract infections, such as the flu or common cold -- up to 5.4 percent of people
  • Cough -- up to 4.6 percent of people (see Tarka Cough)
  • A certain type of irregular heart rhythm (known as AV block) -- up to 3.9 percent of people
  • Constipation -- up to 3.3 percent of people
  • Increased liver enzymes in the blood -- up to 3.2 percent of people.
Other side effects with trandolapril-verapamil ER occurring in more than 1 percent of people include but are not limited to:
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Last reviewed by: Kristi Monson, PharmD;
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