Hypertension Home > Ziac Side Effects
In clinical studies, diarrhea, fatigue, and dizziness were the most common side effects reported with Ziac. Side effects are typically mild and, in most cases, either do not require medical attention or can be treated easily. However, certain problems are potentially serious and should be reported to your healthcare provider, such as lightheadedness or fainting, chest pain, or seizures.
As with any medicine, side effects are possible with Ziac® (bisoprolol and hydrochlorothiazide). However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Ziac. Your healthcare provider can discuss a more complete list of side effects with you.)
Ziac has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and compared to those that occur in another group of people not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
In these studies, the most common side effects seen with Ziac (occurring more frequently with Ziac than with the placebo) included:
- Dizziness -- in up to 5.1 percent of people
- Fatigue -- up to 4.6 percent
- Diarrhea -- up to 4.3 percent.
Other common side effects (occurring in 1.1 to 2.4 percent of people) included:
- Muscle cramps
- Muscle pain
- Impotence (also known as erectile dysfunction or ED)
- Indigestion or heartburn.