Methylsulfonylmethane Dosage

There is no standard recommended dose of methylsulfonylmethane. Clinical studies using the supplement for allergic rhinitis used a dosage of 2600 mg daily, while studies for arthritis used doses ranging from 500 mg three times daily to 2000 mg twice daily. Since a safe and effective methylsulfonylmethane dosage has not been established, it's a good idea to follow the dosing directions on the label of your particular product.

 

An Introduction to Methylsulfonylmethane Dosage

The best dose for methylsulfonylmethane (MSM) for any use has not yet been determined. Because methylsulfonylmethane is a dietary supplement (not a drug), there is little information available to provide guidance about safe and effective methylsulfonylmethane dosages.
 

Reasonable Methylsulfonylmethane Dosing

Most studies of using methylsulfonylmethane for arthritis have used doses ranging from 500 mg three times a day up to 2000 mg twice daily, taken by mouth. For allergic rhinitis (a runny or stuffy nose due to allergies), one study used a methylsulfonylmethane dosage of 2600 mg per day.
 
The best methylsulfonylmethane dosage has not been clearly established for any use. It is reasonable to follow the directions on the label of your particular product. Do not exceed these recommendations unless your healthcare provider specifically instructs you to do so.
 

General Information on Dosing With Methylsulfonylmethane

Some considerations for people taking methylsulfonylmethane include:
 
 
  • Since the manufacturing of dietary supplements (such as methylsulfonylmethane) is not closely regulated, it is important to choose a trustworthy manufacturer for your supplements. It is a good idea to look for the "USP" symbol, since this means that the supplement has been tested and contains the right ingredients in the right amounts.
     
  • If you have any chronic health problems or take any prescription medications, it is probably a good idea to check with your healthcare provider before taking methylsulfonylmethane.
     
  • If you are unsure about anything related to your dosage or methylsulfonylmethane dosing in general, please talk with your healthcare provider.
     
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;